The first and only FDA approved

at-home tDCS treatment for depression.

Flow FL-100 is an FDA-approved prescription medical device for adults with
moderate to severe major depressive disorder that can be used at home

Check eligibility

What is Flow

FL-100?

Flow FL-100 is a prescription medical device intended for the treatment of moderate to severe major depressive disorder in adults 18 years and older. 

It uses transcranial direct current stimulation, or tDCS, and is designed to be used at home as part of a clinician-supervised treatment plan. 

Flow FL-100 may be prescribed as a standalone treatment or alongside antidepressant medication, where clinically appropriate.

FDA-approved device

Prescription-only treatment

Used at home

Clinician supervised

Clinical evidence

Behind Flow FL-100

Flow FL-100 was evaluated in a 10-week, multisite, double-blind, randomized sham-controlled clinical trial in adults with major depressive disorder. In the active treatment group, 57.5% of participants achieved remission at 10 weeks. Flow FL-100 was studied both as monotherapy and as an adjunctive treatment.

Achieved remission at 10 weeks*

57,5%

Clinical trial duration

10 weeks

Patients prescribed Flow internationally since 2019**

60,000+

How to access Flow

Flow FL-100 is available by prescription only and should be used under the supervision of a licensed healthcare professional. There are two ways to start.

Start a virtual consult

Start the process with Upscript, Flow’s telehealth provider. 1 – Complete an online eligibility check 2 – Book a virtual consultation if eligible to continue 3 – If prescribed, Flow FL-100 is shipped to your home

Start a visual consult

Speak to your current provider

Prefer to speak with your own clinician first? 1 – Download the Flow FL-100 information pack 2 – Discuss Flow FL-100 with your healthcare provider 3– Your provider can complete Flow training and prescribe if appropriate

Download provider information

Frequently asked questions

Is Flow safe to use?

Does Flow help with anxiety?

Anxiety is commonly associated with depression, and many Flow users report improvements in both anxiety and mood.
Each week, Flow users complete a questionnaire, and about 66% report reduced feelings of unease after just three weeks of use*.
Since Flow hasn’t been tested as a standalone treatment for anxiety, we recommend it for anxiety relief only if you have depression too.

* Flow real-world data (n=14,383, Apr 2025)

Footnote

*Remission is defined as a score of <10 on MADRS. MADRS remission rate was a secondary endpoint of the study. The primary endpoint reviewed between-group mean difference in HDRS-17 scores and was –2.3 points in favour of the active group (p=0.012).

**International use data. Not all data may be directly comparable to US use. Claims subject to medical, legal and regulatory approval.